Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents

Jian Ren, Naoki Agata, Dongshu Chen, +7

Cancer Cell

Tumor BiologyOncogenic AgentMedicineImmunologyCancer Biology +5

Increased Myeloid Cell Responses to M-CSF and RANKL Cause Bone Loss and Inflammation in SH3BP2 “Cherubism” Mice

Yasuyoshi Ueki, Chin‐Yu Lin, Makoto Senoo, +8

Cell

InflammationImmunologyMyeloid Cell ResponsesOsteoporosisBone Homeostasis +4

Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin C

Naoki Matsumoto, Akiko Ariga, Sakino To‐e, +5

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryPharmaceutical ChemistryBiochemistryMedicine +6

A Phase II Study of Sunitinib in Japanese Patients with Metastatic Renal Cell Carcinoma: Insights into the Treatment, Efficacy and Safety

Hirotsugu Uemura, Nozomi Shinohara, Takeshi Yuasa, +12

Japanese Journal of Clinical Oncology

Overall Survival and Updated Results from a Phase II Study of Sunitinib in Japanese Patients with Metastatic Renal Cell Carcinoma

Yoshihiko Tomita, Nobuo Shinohara, Takeshi Yuasa, +12

Japanese Journal of Clinical Oncology

MUC1 Oncoprotein Blocks Death Receptor–Mediated Apoptosis by Inhibiting Recruitment of Caspase-8

Naoki Agata, Rehan Ahmad, Takeshi Kawano, +3

Cancer Research

Signal TransductionSignaling PathwayMedicineApoptosisImmunology +11

2-(8-Hydroxy-6-Methoxy-1-Oxo-1H-2-Benzopyran-3-yl) Propionic Acid, an Inhibitor of Angiogenesis, Ameliorates Renal Alterations in Obese Type 2 Diabetic Mice

Kunihiro Ichinose, Yohei Maeshima, Yoshihiko Yamamoto, +8

Diabetes

Diabetic MiceImmunologyMetabolic RemodelingDb/db MiceOxidative Stress +20

Characterization of L-Lysine 6-Aminotransferase and Its Structural Gene from Flavobacterium lutescens IFO3084

Tadashi Fujii, Tadashi Narita, Hitosi Agematu, +2

The Journal of Biochemistry

Protein ExpressionL-lysine 6-AminotransferaseBiochemistryStructural GeneLat Activity +10

A novel isocoumarin derivative induces mitotic phase arrest and apoptosis of human multiple myeloma cells

Takeshi Kawano, Naoki Agata, Surender Kharbanda, +2

Cancer Chemotherapy and Pharmacology

MedicineApoptosisCell DeathImmune Checkpoint InhibitorAnti-cancer Agent +3

Antineoplastic effects of chemotherapeutic agents are potentiated by NM-3, an inhibitor of angiogenesis.

Corinne Reimer, Naoki Agata, Jennifer Tammam, +9

PubMed

Chemotherapeutic AgentsAntineoplastic EffectsOncologyAngiogenesisAngiogenesis Inhibitors +13