Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial

Paolo Caraceni, Oliviero Riggio, Paolo Angeli, +90

The Lancet

HepatologyDecompensated CirrhosisLiver PhysiologyGastroenterologyAcute Liver Failure +4

The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology

Jonel Trebicka, Javier Fernández, Mária Papp, +122

Journal of Hepatology

Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

Richard Moreau, Joan Clària, Ferrán Aguilar, +44

Journal of Hepatology

InflammationMetabolic SyndromeAutoimmune DiseaseMitochondrial FunctionPhysiology +10

PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis

Jonel Trebicka, Javier Fernández, Mária Papp, +125

Journal of Hepatology

Clinical features and evolution of bacterial infection-related acute-on-chronic liver failure

Florence Wong, Salvatore Piano, Virendra Singh, +65

Journal of Hepatology

HepatologyAntibioticsLiver PhysiologyClinical FeaturesSepsis +9

Safety of two different doses of simvastatin plus rifaximin in decompensated cirrhosis (LIVERHOPE-SAFETY): a randomised, double-blind, placebo-controlled, phase 2 trial

Elisa Pose, Laura Napoleone, Ahmed Adel Amin, +27

˜The œLancet. Gastroenterology & hepatology

Drug SafetyHepatologyDecompensated CirrhosisLiver PhysiologyPharmacology +6

Efficacy of Albumin Treatment for Patients with Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis

Javier Fernández, Paolo Angeli, Jonel Trebicka, +31

Clinical Gastroenterology and Hepatology

HepatologyGastroenterologySepsisInfections UnrelatedClinical Gastroenterology +4

On-treatment serum albumin level can guide long-term treatment in patients with cirrhosis and uncomplicated ascites

Paolo Caraceni, Manuel Tufoni, Giacomo Zaccherini, +90

Journal of Hepatology

UrologyHepatologyUncomplicated AscitesLiver PhysiologyLong-term Treatment +6

Rhabdomyolysis and myoglobinuria. Association with hypokalemia of renal tubular acidosis

Daniela Campion

JAMA

Endpoints and design of clinical trials in patients with decompensated cirrhosis: Position paper of the LiverHope Consortium

Elsa Solà, Elisa Pose, Daniela Campion, +46

Journal of Hepatology