Nicholas J. Paradis

Mechanistic insight on the remdesivir binding to RNA-Dependent RNA polymerase (RdRp) of SARS-cov-2

Muhammad Arba, Setyanto Tri Wahyudi, Dylan Brunt et al. · Computers in Biology and Medicine · 2020 · 42 citations · Full text

Life Sciences, Biology, Molecular Biology +14

Novel Inhibitors to MmpL3 Transporter of <i>Mycobacterium tuberculosis</i> by Structure-Based High-Throughput Virtual Screening and Molecular Dynamics Simulations

Hetanshi Choksi, Justin Carbone, Nicholas J. Paradis et al. · ACS Omega · 2024 · 17 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +14

Inhibition Mechanism of Anti-TB Drug SQ109: Allosteric Inhibition of TMM Translocation of Mycobacterium Tuberculosis MmpL3 Transporter

Justin Carbone, Nicholas J. Paradis, Lucas Bennet et al. · Journal of Chemical Information and Modeling · 2023 · 14 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Thermodynamic destabilization of azurin by four different tetramethylguanidinium amino acid ionic liquids

Isabella DeStefano, Gabriella DeStefano, Nicholas J. Paradis et al. · International Journal of Biological Macromolecules · 2021 · 12 citations

Natural Sciences, Biochemistry, Chemistry +7

To probe the binding of TMPyP4 to c-MYC G-quadruplex with in water and in imidazolium-based ionic liquids using spectroscopy coupled with molecular dynamics simulations

Nicholas J. Paradis, Austin K. Clark, Hunter Gogoj et al. · Journal of Molecular Liquids · 2022 · 11 citations

Natural Sciences, Chemistry, Physics +14