Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

Laura Albizu, Martin Cottet, Michaela Králíková, +16

Nature Chemical Biology

Signal TransductionMolecular PhysiologyG Protein-coupled ReceptorNatural SciencesReceptor (Biochemistry) +9

Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy

Rita Rahmeh, Marjorie Damian, Martin Cottet, +13

Proceedings of the National Academy of Sciences

Molecular BiologyCell SignalingG ProteinMolecular PhysiologyBiochemistry +15

A Fluorescent Ligand-Binding Alternative Using Tag-lite® Technology

Jurriaan M. Zwier, Thomas Roux, Martin Cottet, +13

SLAS DISCOVERY

Drug TargetEngineeringQuantitative PharmacologyPeptide ScienceMolecular Pharmacology +18

Extended two-photon microscopy in live samples with Bessel beams: steadier focus, faster volume scans, and simpler stereoscopic imaging

Gabrielle Thériault, Martin Cottet, Annie Castonguay, +2

Frontiers in Cellular Neuroscience

Engagement of the GABA to KCC2 Signaling Pathway Contributes to the Analgesic Effects of A₃AR Agonists in Neuropathic Pain

Amanda Ford, Annie Castonguay, Martin Cottet, +10

Journal of Neuroscience

BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues

Martin Cottet, Orestis Faklaris, Damien Maurel, +5

Frontiers in Endocrinology

A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate

Angélique Levoye, Jurriaan M. Zwier, Agnieszka Jaracz‐Ros, +9

Frontiers in Endocrinology

Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization

Francesco Ferrini, Jimena Pérez-Sánchez, Samuel Ferland, +10

Nature Communications

Untangling dopamine-adenosine receptor assembly in experimental parkinsonism

Víctor Fernández‐Dueñas, Jaume Taura, Martin Cottet, +9

Disease Models & Mechanisms

Selective Fluorescent Nonpeptidic Antagonists For Vasopressin V₂GPCR: Application To Ligand Screening and Oligomerization Assays.

Stéphanie Loison, Martin Cottet, Hélène Orcel, +9

Journal of Medicinal Chemistry

EngineeringOrganic ChemistryPeptide ScienceAvp V₂rPharmaceutical Chemistry +20