A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

Manuel Irimia, Robert J. Weatheritt, Jonathan D. Ellis, +14

Cell

Developmental BiologyMolecular NeuroscienceSyndromic AutismAutistic BrainsAutism +8

Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain

Bushra Raj, Daniel E. Wagner, Aaron McKenna, +5

Nature Biotechnology

Cell LineageHuman CellDevelopmental BiologyCell TypesCell Division +11

Regulation of Vertebrate Nervous System Alternative Splicing and Development by an SR-Related Protein

John A. Calarco, Simone Superina, Dave O’Hanlon, +10

Cell

Transcriptional RegulationMolecular NeuroscienceDevelopmental BiologyMolecular RegulationGenetics +6

An alternative splicing event amplifies evolutionary differences between vertebrates

Serge Gueroussov, Thomas Gonatopoulos-Pournatzis, Manuel Irimia, +4

Science

Cross-Regulation between an Alternative Splicing Activator and a Transcription Repressor Controls Neurogenesis

Bushra Raj, Dave O’Hanlon, John P. Vessey, +5

Molecular Cell

Transcriptional RegulationDevelopmental BiologyGeneticsRna SplicingGene Regulation +6

A Global Regulatory Mechanism for Activating an Exon Network Required for Neurogenesis

Bushra Raj, Manuel Irimia, Ulrich Braunschweig, +9

Molecular Cell

NeuroregenerationDevelopmental BiologySignal TransductionExon Network RequiredNeurogenesis +7

Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons

Thomas Gonatopoulos-Pournatzis, Mingkun Wu, Ulrich Braunschweig, +11

Molecular Cell

Molecular NeuroscienceGenome-wide Crispr-cas9 InterrogationSyndromic AutismGeneticsRna Splicing +8

Emergence of Neuronal Diversity during Vertebrate Brain Development

Bushra Raj, Jeffrey A. Farrell, Jialin Liu, +8

Neuron

Developmental BiologyBrain StructureDevelopmental Cognitive NeuroscienceNeuroanatomyBrain Development +7

Large-scale reconstruction of cell lineages using single-cell readout of transcriptomes and CRISPR–Cas9 barcodes by scGESTALT

Bushra Raj, James A. Gagnon, Alexander F. Schier

Nature Protocols

Single Cell SequencingMedicineGeneticsSingle-cell GenomicsLarge-scale Reconstruction +9

Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain by scGESTALT

Bushra Raj, Daniel E. Wagner, Aaron McKenna, +5

Simultaneous Single-cell ProfilingGeneticsTranscriptomics TechnologyGenomicsCell Types +24