Stephen Van Dien

Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

Harry Yim, Robert J. Haselbeck, Wei Niu et al. · Nature Chemical Biology · 2011 · 1.1K citations

Biomanufacturing, Biosynthesis, Engineering +9

Metabolic flux elucidation for large-scale models using 13C labeled isotopes

Patrick F. Suthers, Anthony P. Burgard, Madhukar S. Dasika et al. · Metabolic Engineering · 2007 · 102 citations · Full text

Isotope Analysis, Biology, Biogeochemistry +15

Identification of metabolic engineering targets for the enhancement of 1,4-butanediol production in recombinant E. coli using large-scale kinetic models

Stefano Andreozzi, Anirikh Chakrabarti, Keng Cher Soh et al. · Metabolic Engineering · 2016 · 91 citations · Full text

1,4-Butanediol Production, Biomanufacturing, Biosynthesis +13

Determination of metabolic flux changes during fed-batch cultivation from measurements of intracellular amino acids by LC-MS/MS

Shintaro Iwatani, Stephen Van Dien, Kazutaka Shimbo et al. · Journal of Biotechnology · 2006 · 76 citations

Fed-batch Cultivation, Biochemistry, Bioanalysis +11

Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol. Nat Chem Biol

Harry Yim, Robert J. Haselbeck, Wei Niu et al. · 2011 · 45 citations

Biomanufacturing, Engineering, Biochemical Engineering +11