John B. Tobin

A Low-Barrier Hydrogen Bond in the Catalytic Triad of Serine Proteases

Perry A. Frey, Sean A. Whitt, John B. Tobin · Science · 1994 · 735 citations

Life Sciences, Biochemistry, Chemistry +17

Low-Barrier Hydrogen Bonding in Molecular Complexes Analogous to Histidine and Aspartate in the Catalytic Triad of Serine Proteases

John B. Tobin, Sean A. Whitt, Constance S. Cassidy et al. · Biochemistry · 1995 · 89 citations

Natural Sciences, Biochemistry, Chemistry +17

Electrostatic Acceleration of Enolization in Cationic Ketones

John B. Tobin, Perry A. Frey · Journal of the American Chemical Society · 1996 · 33 citations

Natural Sciences, Chemistry, Catalysis +7

Protonation of Phenyl(trimethylsilyl)acetylene: A Surprisingly Weak Stabilization of a Carbocation by a β‐Trimethylsilyl Group

A. J. Kresge, John B. Tobin · Angewandte Chemie International Edition in English · 1993 · 26 citations

Natural Sciences, Chemistry, Chemical Kinetics +6

Rapid hydrogen exchange at the acetyl (C2) methyl group of acetylthiamine pyrophosphate

Christopher J. Halkides, Perry A. Frey, John B. Tobin · Journal of the American Chemical Society · 1993 · 24 citations

Natural Sciences, Biochemistry, Chemistry +7