Sharon G. Bernard

Pharmacological validation of targets regulating CD14 during macrophage differentiation

Gisela Jimenez‐Duran, Rosario Luque-Martin, Meghana Patel et al. · EBioMedicine · 2020 · 50 citations · Full text

IFN-γ Drives Human Monocyte Differentiation into Highly Proinflammatory Macrophages That Resemble a Phenotype Relevant to Psoriasis

Rosario Luque-Martin, Davina C. Angell, Mathias Kalxdorf et al. · The Journal of Immunology · 2021 · 49 citations

Fide Macrophages, Innate Immune System, Immune Regulation +17

Structure-Based Design of a Bromodomain and Extraterminal Domain (BET) Inhibitor Selective for the N-Terminal Bromodomains That Retains an Anti-inflammatory and Antiproliferative Phenotype

Christopher R. Wellaway, Paul Bamborough, Sharon G. Bernard et al. · Journal of Medicinal Chemistry · 2020 · 46 citations · Full text

Immunology, Molecular Biology, Biological Therapy +17

Discovery of a Novel Bromodomain and Extra Terminal Domain (BET) Protein Inhibitor, I-BET282E, Suitable for Clinical Progression

Katherine L. Jones, Dominic M. Beaumont, Sharon G. Bernard et al. · Journal of Medicinal Chemistry · 2021 · 39 citations · Full text

Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis

Rosario Luque-Martin, Jan Van den Bossche, Rebecca C. Furze et al. · Frontiers in Pharmacology · 2019 · 22 citations · Full text