Concepedia

Joseph M. Perchiacca

JM

Statistics

Publications

5

Citations

519

H-Index

5

Active since

2011

Affiliations

Rensselaer Polytechnic Institute(Current)

Joseph M. Perchiacca is an author at Rensselaer Polytechnic Institute specializing in antibody engineering, molecular biology, and antibodies.

Publications per year

2011–2014

5

Publications

5

Structure-based design of conformation- and sequence-specific antibodies against amyloid β

Joseph M. Perchiacca, Ali Reza A. Ladiwala, Moumita Bhattacharya et al. · Proceedings of the National Academy of Sciences · 2011 · 144 citations

Life Sciences, Biochemistry, Molecular Biology +17

Rational design of potent domain antibody inhibitors of amyloid fibril assembly

Ali Reza A. Ladiwala, Moumita Bhattacharya, Joseph M. Perchiacca et al. · Proceedings of the National Academy of Sciences · 2012 · 107 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Aggregation-resistant domain antibodies engineered with charged mutations near the edges of the complementarity-determining regions

Joseph M. Perchiacca, Ali Reza A. Ladiwala, M. Bhattacharya et al. · Protein Engineering Design and Selection · 2012 · 107 citations · Full text

Pharmacy, Bioengineering, Molecular Biology +17

Mutational analysis of domain antibodies reveals aggregation hotspots within and near the complementarity determining regions

Joseph M. Perchiacca, Moumita Bhattacharya, Peter M. Tessier · Proteins Structure Function and Bioinformatics · 2011 · 100 citations

Pharmacy, Immunology, Molecular Biology +17

Optimal charged mutations in the complementarity-determining regions that prevent domain antibody aggregation are dependent on the antibody scaffold

Joseph M. Perchiacca, C. C. Lee, Peter M. Tessier · Protein Engineering Design and Selection · 2014 · 61 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +15

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