John Ramphal

A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.

James G. Christensen, Randall Schreck, Jon Burrows et al. · PubMed · 2003 · 497 citations

Medicine, Oncology, Pharmacology +15

Lipoxins and Related Eicosanoids: Biosynthesis, Biological Properties, and Chemical Synthesis

K. C. Nicolaou, John Ramphal, Nicos A. Petasis et al. · Angewandte Chemie International Edition in English · 1991 · 104 citations

Life Sciences, Biochemistry, Chemistry +13

Structure-Activity Relationships of Sialyl Lewis x-Containing Oligosaccharides. 1. Effect of Modifications of the Fucose Moiety

John Ramphal, Z L Zheng, L E Walker et al. · Journal of Medicinal Chemistry · 1994 · 82 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Structure-Based design and discovery of novel inhibitors of protein tyrosine phosphatases

Ping Huang, John Ramphal, James Cheng‐Chung Wei et al. · Bioorganic & Medicinal Chemistry · 2003 · 57 citations

Life Sciences, Biochemistry, Medicinal Chemistry +15

Ligand Interactions with E-Selectin. Identification of a New Binding Site for Recognition of <i>N</i>-Acyl Aromatic Glucosamine Substituents of Sialyl Lewis X

John Ramphal, Mariann Hiroshige, Boliang Lou et al. · Journal of Medicinal Chemistry · 1996 · 36 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17