Massively parallel digital transcriptional profiling of single cells

Grace Zheng, Jessica M. Terry, Phillip Belgrader, +30

Nature Communications

Massively parallel digital transcriptional profiling of single cells

Grace Zheng, Jessica M. Terry, Phillip Belgrader, +29

ImmunologySingle CellsTranscriptomics TechnologyImmune SystemGene Expression Profiling +15

High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging

Shanshan He, Ruchir Bhatt, Carl Brown, +35

Nature Biotechnology

Tissue ImagingEngineeringMedical ImagingMicroscopyMedicine +10

Structure and mechanism of human DNA polymerase η

Christian Biertümpfel, Ye Zhao, Yuji Kondo, +7

Nature

Polymerase Chain ReactionNucleic Acid ChemistryDnaNatural SciencesOligonucleotide +4

Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass

Young‐Sam Lee, Mark Gregory, Wei Yang

Proceedings of the National Academy of Sciences

Molecular RegulationPol ζMolecular BiologyMolecular ResearchTranscriptional Regulation +19

Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin

Ye Zhao, Christian Biertümpfel, Mark Gregory, +3

Proceedings of the National Academy of Sciences

Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η

Ye Zhao, Mark Gregory, Christian Biertümpfel, +3

Proceedings of the National Academy of Sciences

ChromatinNucleic Acid ChemistrySomatic VariantSomatic HypermutationProtein Assembly +13

High-plex Multiomic Analysis in FFPE at Subcellular Level by Spatial Molecular Imaging

Shanshan He, Ruchir Bhatt, Carl Brown, +35

EngineeringAutomated InstrumentMolecular BiologySpatial Molecular ImagingSpatial Omics +25

Targeted single molecule mutation detection with massively parallel sequencing

Mark Gregory, Jessica A. Bertout, Nolan G. Ericson, +5

Nucleic Acids Research

EngineeringGeneticsMolecular BiologyMolecular GeneticsGenomics +18

Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage

Mark Gregory, Ga Young Park, Timothy C. Johnstone, +3

Proceedings of the National Academy of Sciences