Jaein Shin

Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids

Hongwon Kim, Hyeok Ju Park, Hwan Geun Choi et al. · Stem Cell Reports · 2019 · 325 citations · Full text

Parkinson Disease, Degenerative Disease, Midbrain Organoids +2

Electromagnetized gold nanoparticles mediate direct lineage reprogramming into induced dopamine neurons in vivo for Parkinson's disease therapy

Junsang Yoo, Euiyeon Lee, Hee Young Kim et al. · Nature Nanotechnology · 2017 · 143 citations

Nanoparticles, Nanomedicine, Engineering +9

CRISPR/dCas9-Dnmt3a-mediated targeted DNA methylation of APP rescues brain pathology in a mouse model of Alzheimer’s disease

Hanseul Park, Jaein Shin, Yun-Kyung Kim et al. · Translational Neurodegeneration · 2022 · 58 citations · Full text

Modelling APOE ɛ3/4 allele-associated sporadic Alzheimer’s disease in an induced neuron

Hongwon Kim, Junsang Yoo, Jaein Shin et al. · Brain · 2017 · 29 citations · Full text

Direct Lineage Conversion, Neurochemical Biomarkers, Amyloid Precursor Protein +19

Bifidobacterium bifidum BGN4 and Bifidobacterium longum BORI promotes neuronal rejuvenation in aged mice

Hongwon Kim, Jaein Shin, Sumin Kim et al. · Biochemical and Biophysical Research Communications · 2022 · 23 citations

Neurodegenerative Diseases, Neural Aging, Neuroprotection +8