Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins

Samuel E. DePrimo, Carlo L. Bello, John Smeraglia, +5

Journal of Translational Medicine

EBF Recommendation on the Validation of Bioanalytical Methods for Dried Blood Spots

Philip Timmerman, Steve White, Susanne Globig, +3

Bioanalysis

EngineeringPathologyDermatologyEuropean Bioanalysis ForumEbf Recommendation +19

Effect of food on the pharmacokinetics of sunitinib malate (SU11248), a multi-targeted receptor tyrosine kinase inhibitor: results from a phase I study in healthy subjects

Carlo L. Bello, Laurie Sherman, Jihao Zhou, +4

Anti-Cancer Drugs

NutritionOral BioavailabilityHealthy SubjectsDietary ExposureChemoprevention Strategy +15

Matrix effects and selectivity issues in LC-MS-MS

John Smeraglia, S. F. Baldrey, David G. Watson

Chromatographia

Matrix EffectsResonanceMatrix MethodMatrix TheoryMatrix Analysis

2015 White Paper on Recent Issues in Bioanalysis: Focus on New Technologies and Biomarkers (Part 3 – Lba, Biomarkers and Immunogenicity)

Lakshmi Amaravadi, An Song, Heather Myler, +46

Bioanalysis

2017 White Paper on Recent Issues in Bioanalysis: A Global Perspective on Immunogenicity Guidelines & Biomarker Assay Performance (Part 3 – Lba: Immunogenicity, Biomarkers and PK Assays)

Shalini Gupta, Susan Richards, Lakshmi Amaravadi, +64

Bioanalysis

ImmunohematologyPk AssaysWhite PaperImmunologyBiological Mass Spectrometry +25

2016 White Paper on Recent Issues in Bioanalysis: Focus on Biomarker Assay Validation (BAV): (Part 3 – Lba, Biomarkers and Immunogenicity)

Susan Richards, Lakshmi Amaravadi, Renuka Pillutla, +50

Bioanalysis

EngineeringWhite PaperImmunologyBiological Mass SpectrometryPathology +31

2014 White Paper on Recent Issues in Bioanalysis: A Full Immersion in Bioanalysis (Part 2 – Hybrid LBA/LCMS, ELN & Regulatory Agencies’ Input)

Dawn Dufield, Hendrik Neubert, Fabio Garofolo, +48

Bioanalysis

EngineeringWhite PaperInvolved LcmsFull ImmersionBioanalysis +23

2014 White Paper on Recent Issues in Bioanalysis: A Full Immersion in Bioanalysis (Part 1 – Small Molecules by LCMS)

Eric Fluhler, Fabio Garofolo, Isabelle Dumont, +40

Bioanalysis

EngineeringWhite PaperFull ImmersionBioanalysisRegulatory Agencies +22

Analysis of circulating biomarkers of sunitinib malate in patients with unresectable neuroendocrine tumors (NET): VEGF, IL-8, and soluble VEGF receptors 2 and 3

Carlo L. Bello, Samuel E. DePrimo, Chad Friece, +7

Journal of Clinical Oncology

Endocrine OncologyTumoral PathologySunitinib MalateUnresectable Neuroendocrine TumorsPlasma Levels +13