John Colgan

Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

Shigeki Chiba, Muhammad Baghdadi, Hisaya Akiba et al. · Nature Immunology · 2012 · 812 citations · Full text

Cancer Immunosurveillance, Receptor Tim-3, Immunology +12

TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs

Brygida Bisikirska, John Colgan, Jeremy Luban et al. · Journal of Clinical Investigation · 2005 · 338 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +17

Cyclophilin A Regulates TCR Signal Strength in CD4+ T Cells via a Proline-Directed Conformational Switch in Itk

John Colgan, Mohammed Asmal, Martha R. Neagu et al. · Immunity · 2004 · 222 citations · Full text

Proline-directed Conformational Switch, Signal Transduction, Natural Sciences +10

Human Immunodeficiency Virus Type 1 Gag Polyprotein Multimerization Requires the Nucleocapsid Domain and RNA and Is Promoted by the Capsid-Dimer Interface and the Basic Region of Matrix Protein

Mark T. Burniston, Andrea Cimarelli, John Colgan et al. · Journal of Virology · 1999 · 185 citations · Full text

TFIID can be rate limiting in vivo for TATA-containing, but not TATA-lacking, RNA polymerase II promoters.

John Colgan, James L. Manley · Genes & Development · 1992 · 150 citations · Full text

Engineering, Genetics, Drosophila Schneider Cells +16