<i>Dmrt1</i>, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation

Christopher S. Raymond, Mark W. Murphy, Maeve O’Sullivan, +2

Genes & Development

SpermatogenesisGeneticsGenomic MechanismMolecular GeneticsReproductive Biology +19

DMRT1 prevents female reprogramming in the postnatal mammalian testis

Clinton K. Matson, Mark W. Murphy, Aaron L. Sarver, +3

Nature

InfertilityDevelopmental BiologyGerm Cell FateGeneticsFemale Reproductive System +8

The Mammalian Doublesex Homolog DMRT1 Is a Transcriptional Gatekeeper that Controls the Mitosis versus Meiosis Decision in Male Germ Cells

Clinton K. Matson, Mark W. Murphy, Michael D. Griswold, +3

Developmental Cell

SpermatogenesisChromatinGerm CellCell DivisionGenetics +10

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

Anthony D. Krentz, Mark W. Murphy, Shinseog Kim, +10

Proceedings of the National Academy of Sciences

SpermatogenesisGeneticsCell ProliferationEpigeneticsTumor Biology +19

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary

Anthony D. Krentz, Mark W. Murphy, Aaron L. Sarver, +3

Developmental Biology

OocyteTranscriptional RegulationDevelopmental BiologyOogenesisDevelopmental Genetics +10

An ancient protein-DNA interaction underlying metazoan sex determination

Mark W. Murphy, John K. Lee, Sandra Rojo, +9

Nature Structural & Molecular Biology

BiologyAncient Protein-dna InteractionSex DeterminationGeneticsSex Differences +6

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis

Mark W. Murphy, Aaron L. Sarver, Daren A. Rice, +6

Proceedings of the National Academy of Sciences

In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures

Massilva Rahmoun, Rowena Lavery, Sabine Laurent-Chaballier, +15

Nucleic Acids Research

SpermatogenesisGeneticsGenomic MechanismTarget GenesMolecular Genetics +15

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA

Mark W. Murphy, David Zarkower, Vivian J. Bardwell

BMC Molecular Biology

The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis

Teng Zhang, Mark W. Murphy, Micah D. Gearhart, +2

Development

SpermatogenesisFertilityGeneticsMrna ProfilingReproductive Biology +21