Joana Catarina Macedo

FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence

Joana Catarina Macedo, Sara Vaz, Björn Bakker et al. · Nature Communications · 2018 · 130 citations · Full text

Chromosome mis-segregation and cytokinesis failure in trisomic human cells

Joshua M. Nicholson, Joana Catarina Macedo, Aaron Mattingly et al. · eLife · 2015 · 105 citations · Full text

Chromatin, Genome Instability, Cell Division +13

In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan

Rui Ribeiro, Joana Catarina Macedo, Madalena Costa et al. · Nature Aging · 2022 · 78 citations

Lifespan Extension, Developmental Biology, Aging +12

Small‐molecule inhibition of aging‐associated chromosomal instability delays cellular senescence

Monika Barroso‐Vilares, Joana Catarina Macedo, M. Reis et al. · EMBO Reports · 2020 · 51 citations · Full text

Chromatin, Genome Instability, Developmental Biology +13

The antitumor efficacy of monomeric disintegrin obtustatin in S-180 sarcoma mouse model

Nariné Ghazaryan, Naira Movsisyan, Joana Catarina Macedo et al. · Investigational New Drugs · 2019 · 21 citations

Medicine, Immunology, Pharmacology +5