On the Seeding and Oligomerization of pGlu-Amyloid Peptides (<i>in vitro</i>)

Stephan Schilling, Thomas Lauber, Michael Schaupp, +4

Biochemistry

Neurodegenerative DiseasesAlzheimer's DiseaseBiochemistryProtein FoldingPglu Peptides +12

Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor

C. Parthier, Martin Kleinschmidt, Piotr Neumann, +7

Proceedings of the National Academy of Sciences

Crystal StructureGlycobiologyFood IntakeMolecular BiologyInsulin Signaling +18

Pyroglutamate Formation Influences Solubility and Amyloidogenicity of Amyloid Peptides

Dagmar Schlenzig, Susanne Manhart, Yeliz Cinar, +6

Biochemistry

Alzheimer's DiseaseBiochemistryProtein FoldingN-terminal PgluMedicine +7

Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions

Stephan Schilling, Torsten Hoffmann, Susanne Manhart, +2

FEBS Letters

Reversal of islet GIP receptor down-regulation and resistance to GIP by reducing hyperglycemia in the Zucker rat

Shalea Piteau, Amy Olver, Su‐jin Kim, +8

Biochemical and Biophysical Research Communications

Metabolic SyndromeNeuropeptidesInsulin SignalingMolecular PhysiologyZucker Rat +10

Dipeptidyl Peptidase IV-Resistant [<scp>d</scp>-Ala2]Glucose-Dependent Insulinotropic Polypeptide (GIP) Improves Glucose Tolerance in Normal and Obese Diabetic Rats

Simon A. Hinke, Richard W. Gelling, Raymond A. Pederson, +4

Diabetes

Peptide TherapeuticsGlucose ToleranceInsulin SignalingObesityMetabolic Syndrome +17

Identification of a bioactive domain in the amino-terminus of glucose-dependent insulinotropic polypeptide (GIP)

Simon A. Hinke, Susanne Manhart, Nathalie Pamir, +4

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Glucose-dependent Insulinotropic PolypeptideBiochemistryG Protein-coupled ReceptorPhysiologyDiabetes +3

Substrate Specificity of Glutaminyl Cyclases from Plants and Animals

Stephan Schilling, Susanne Manhart, T. Hoffmann, +3

Biological Chemistry

Rigidity and Flexibility of Dipeptidyl Peptidase IV: Crystal Structures of and Docking Experiments with DPIV

Michael H. Engel, Torsten Hoffmann, Susanne Manhart, +5

Journal of Molecular Biology

Protein FoldingMedicinePeptoidMolecular BiologyConformational Study +6

Heterologous Expression and Characterization of Human Glutaminyl Cyclase:  Evidence for a Disulfide Bond with Importance for Catalytic Activity

Stephan Schilling, Torsten Hoffmann, Fred Rosche, +3

Biochemistry

GlycobiologyMolecular BiologyEnzymatic ModificationHeterologous ExpressionDisulfide Bond +14