Andrew J. Maloney

Mechanistic model for production of recombinant adeno-associated virus via triple transfection of HEK293 cells

Tam Nguyen, Sha Sha, Moo Sun Hong et al. · Molecular Therapy — Methods & Clinical Development · 2021 · 97 citations · Full text

A Virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib Drug Substance Intermediate, Part 1: CDI-Promoted Amide Bond Formation

Elçin Içten, Andrew J. Maloney, Matthew G. Beaver et al. · Organic Process Research & Development · 2020 · 36 citations

Combinatorial Chemistry, Engineering, Process Development +25

A Virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib Drug Substance Intermediate, Part 3: Manganese-Catalyzed Asymmetric Epoxidation, Crystallization, and Filtration

Andrew J. Maloney, Elçin Içten, Gerard Capellades et al. · Organic Process Research & Development · 2020 · 32 citations

Engineering, Process Development, Chemistry +18

A Virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib Drug Substance Intermediate, Part 2: Enone Synthesis via a Barbier-Type Grignard Process

Elçin Içten, Andrew J. Maloney, Matthew G. Beaver et al. · Organic Process Research & Development · 2020 · 24 citations

Bioorganic Chemistry, Engineering, Medicinal Chemistry +19

Macroscopic modeling of bioreactors for recombinant protein producing <i>Pichia pastoris</i> in defined medium

Moo Sun Hong, M. Lourdes Velez‐Suberbie, Andrew J. Maloney et al. · Biotechnology and Bioengineering · 2020 · 19 citations · Full text