Michael A. Uhouse

A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease

Andrew M. Tidball, Miles R. Bryan, Michael A. Uhouse et al. · Human Molecular Genetics · 2014 · 69 citations · Full text

Neurochemical Biomarkers, Manganese Exposure, Redox Biology +20

Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model

Terry Jo Bichell, Michał Węgrzynowicz, K. Grace Tipps et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2017 · 43 citations · Full text

Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status

Kevin K. Kumar, Cody R. Goodwin, Michael A. Uhouse et al. · Metallomics · 2015 · 33 citations · Full text

Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line

Miles R. Bryan, Michael A. Uhouse, Kristen D. Nordham et al. · NeuroToxicology · 2017 · 32 citations · Full text

Cell Physiology, Mitophagy, Signal Transduction +15

Manganese Acts upon Insulin/IGF Receptors to Phosphorylate AKT and Increase Glucose Uptake in Huntington’s Disease Cells

Miles R. Bryan, Kristen D. Nordham, Daniel I.R. Rose et al. · Molecular Neurobiology · 2019 · 30 citations · Full text

Molecular Physiology, Biochemistry, Increase Glucose Uptake +9