Sophie Le Trionnaire

AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro

Bartosz Szczęsny, Katalin Módis, Kazunori Yanagi et al. · Nitric Oxide · 2014 · 282 citations · Full text

Reductive Stress, Mitochondrial Dna Integrity, Endothelial Cells +7

The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor, (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)decyl)triphenylphosphonium bromide (AP39)

Sophie Le Trionnaire, Alexis Perry, Bartosz Szczęsny et al. · MedChemComm · 2014 · 124 citations

Triphenylphosphonium Bromide, Functional Evaluation, Mitochondrial Dysfunction +19

Phagocytosis depends on TRPV2-mediated calcium influx and requires TRPV2 in lipids rafts: alteration in macrophages from patients with cystic fibrosis

Manuella Lévêque, Aubin Penna, Sophie Le Trionnaire et al. · Scientific Reports · 2018 · 76 citations · Full text

Soluble CD14 acts as a DAMP in human macrophages: origin and involvement in inflammatory cytokine/chemokine production

Manuella Lévêque, Karin Simonin-Le Jeune, S. Jouneau et al. · The FASEB Journal · 2017 · 46 citations · Full text