In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse

Bo Chang, Hemant Khanna, Norman L. Hawes, +17

Human Molecular Genetics

Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio‐marker of fibroproliferative disease?

Andrew Leask, Sunil K. Parapuram, Shiwen Xu, +1

Journal of Cell Communication and Signaling

Ccn2 Gene RegulationImmunologyPathologyCell ProliferationInflammation +17

RPGR-ORF15, Which Is Mutated in Retinitis Pigmentosa, Associates with SMC1, SMC3, and Microtubule Transport Proteins

Hemant Khanna, Toby W. Hurd, Concepción Lillo, +8

Journal of Biological Chemistry

Photoreceptor CellSignal TransductionRetinaProtein FunctionRetinitis Pigmentosa +12

Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines

Aniruddha Choudhury, Jehad Charo, Sunil K. Parapuram, +4

International Journal of Cancer

Loss of PTEN Expression by Dermal Fibroblasts Causes Skin Fibrosis

Sunil K. Parapuram, Shiwen Xu, Christopher G. Elliott, +6

Journal of Investigative Dermatology

FibrosisCutaneous BiologyPten ExpressionPathologyWound Healing +5

Mutations in TOPORS Cause Autosomal Dominant Retinitis Pigmentosa with Perivascular Retinal Pigment Epithelium Atrophy

Christina Chakarova, Myrto Papaioannou, Hemant Khanna, +23

The American Journal of Human Genetics

Ocular DiseaseRetinaOphthalmologyGenetic DisorderGenetics +5

Requirement of transforming growth factor β–activated kinase 1 for transforming growth factor β–induced α‐smooth muscle actin expression and extracellular matrix contraction in fibroblasts

Shiwen Xu, Sunil K. Parapuram, Daphne Pala, +6

Arthritis & Rheumatism

Differential Effects of TGFβ and Vitreous on the Transformation of Retinal Pigment Epithelial Cells

Sunil K. Parapuram, Binyue Chang, Lei Li, +5

Investigative Ophthalmology & Visual Science

Retinitis Pigmentosa GTPase Regulator (RPGR) protein isoforms in mammalian retina: Insights into X-linked Retinitis Pigmentosa and associated ciliopathies

Shirley He, Sunil K. Parapuram, Toby W. Hurd, +4

Vision Research

Photoreceptor CellSignal TransductionRetinaOphthalmologyX-linked Retinitis Pigmentosa +5

Loss of PTEN expression by mouse fibroblasts results in lung fibrosis through a CCN2-dependent mechanism

Sunil K. Parapuram, Katherine Thompson, Matthew Tsang, +4

Matrix Biology

InflammationFibrosisLung InflammationPten ExpressionCell Death +9