Disha M. Gandhi

Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids

Nilisha Pokhrel, Sofia Origanti, Eric Parker Davenport et al. · Nucleic Acids Research · 2017 · 51 citations · Full text

Protein Assembly, Real-time Kinetics, Molecular Biology +17

Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D₃ Dopamine Receptor Agonist

Amy E. Moritz, R. Benjamin Free, Warren S. Weiner et al. · Journal of Medicinal Chemistry · 2020 · 25 citations · Full text

Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels

Chris Dockendorff, Disha M. Gandhi, Ian H. Kimball et al. · Biochemistry · 2018 · 19 citations · Full text

Characterization of Protease-Activated Receptor (PAR) ligands: Parmodulins are reversible allosteric inhibitors of PAR1-driven calcium mobilization in endothelial cells

Disha M. Gandhi, Mark W. Majewski, Ricardo Rosas et al. · Bioorganic & Medicinal Chemistry · 2018 · 18 citations · Full text

Molecular Pharmacology, Molecular Physiology, Signal Transduction +13

The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability

Disha M. Gandhi, Ricardo Rosas, Eric Greve et al. · Bioorganic & Medicinal Chemistry · 2019 · 16 citations · Full text

Inflammation, Parmodulin Nrd-21, Cytokine +11