George Panayotou

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

Carola Ponzetto, Alberto Bardelli, Zhen Zhu et al. · Cell · 1994 · 987 citations

Signal Transduction, Signaling Pathway, Medicine +7

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

Masayuki Otsu, I. Hiles, Ivan Gout et al. · Cell · 1991 · 784 citations

Kd Proteins, Signal Transduction, Signaling Pathway +13

Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit

I. Hiles, Masayuki Otsu, Stefano Volinia et al. · Cell · 1992 · 696 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +10

Wortmannin Inactivates Phosphoinositide 3-Kinase by Covalent Modification of Lys-802, a Residue Involved in the Phosphate Transfer Reaction

Matthias P. Wymann, Ginette Bulgarelli-Leva, Marketa Zvelebil et al. · Molecular and Cellular Biology · 1996 · 677 citations · Full text

Signal Transduction, Biochemistry, Natural Sciences +13

Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.

Matthew J. Bottomley, E. Querfurth, Marketa Zvelebil et al. · The EMBO Journal · 1996 · 564 citations · Full text

Molecular Pharmacology, Distinct Specificity, Signal Transduction +12