Inactivation properties of voltage-gated K+ channels altered by presence of β-subunit

Jens Rettig, Stefan H. Heinemann, Frank Wunder, +4

Nature

Signal TransductionBiochemistryInactivation PropertiesMedicineSynaptic Transmission +5

Immunohistochemical Localization of Five Members of the K_V1 Channel Subunits: Contrasting Subcellular Locations and Neuron‐specific Co‐localizations in Rat Brain

Rüdiger W. Veh, Ralf Lichtinghagen, Sabine Sewing, +3

European Journal of Neuroscience

Distribution of high-conductance Ca(2+)-activated K+ channels in rat brain: targeting to axons and nerve terminals

HG Knaus, Christoph Schwarzer, RO Koch, +6

Journal of Neuroscience

NO‐ and haem‐independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle

Johannes‐Peter Stasch, Péter Schmidt, Cristina Alonso‐Alija, +12

British Journal of Pharmacology

Haem‐independent ActivationCardiovascular PharmacologyPharmacotherapyChemical BiologyMolecular Pharmacology +22

Characterization of a Shaw-related potassium channel family in rat brain.

Jens Rettig, Frank Wunder, Martin Stocker, +7

The EMBO Journal

ChannelopathiesCellular NeurobiologyHyperpolarization (Biology)NeurophysiologyNeuroanatomy +13

Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure

Markus Follmann, Jens Ackerstaff, Gorden Redlich, +21

Journal of Medicinal Chemistry

Medicinal ChemistryHeart FailureChronic Heart FailureCardiomyopathyCardiovascular Disease +13

Functional expression of a rat homologue of the voltage gated either á go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart.

Jost Ludwig, Heinrich Terlau, Frank Wunder, +5

The EMBO Journal

Activation KineticsSignal TransductionMolecular NeuroscienceMolecular PhysiologyNeurophysiology +12

Discovery of Riociguat (BAY 63‐2521): A Potent, Oral Stimulator of Soluble Guanylate Cyclase for the Treatment of Pulmonary Hypertension

Joachim Mittendorf, Stefan Weigand, Cristina Alonso‐Alija, +13

ChemMedChem

Molecular PharmacologyPulmonary Arterial HypertensionBiochemistryMedicineDrug Discovery +12

Engineering of a red-light–activated human cAMP/cGMP-specific phosphodiesterase

Carlos Gasser, Sandra Taiber, Chen-Min Yeh, +5

Proceedings of the National Academy of Sciences

Identification of Residues Crucially Involved in the Binding of the Heme Moiety of Soluble Guanylate Cyclase

Péter Schmidt, Matthias Schramm, H. Schröder, +2

Journal of Biological Chemistry