Michele R. Stabile

Site-Directed Mutagenesis Combined with Chemical Modification as a Strategy for Altering the Specificity of the S₁ and S₁‘ Pockets of Subtilisin <i>Bacillus lentus</i>

Grace DeSantis, Per Berglund, Michele R. Stabile et al. · Biochemistry · 1998 · 45 citations

Life Sciences, Biochemistry, Molecular Biology +17

Chemical Modification of Cysteine Mutants of Subtilisin <i>Bacillus lentus</i> Can Create Better Catalysts Than the Wild-Type Enzyme

Per Berglund, Grace DeSantis, Michele R. Stabile et al. · Journal of the American Chemical Society · 1997 · 39 citations

Life Sciences, Biochemistry, Microbiology +9

Probing the specificity of the S1 binding site of M222 mutants of subtilisin B. lentus with boronic acid inhibitors

Michele R. Stabile, Wei‐Shiang Lai, Grace DeSantis et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 36 citations

Life Sciences, Biochemistry, Molecular Biology +6

Intramolecular Diels–Alder reactions of the furan diene (IMDAF); rapid construction of highly functionalised isoquinoline skeletons

Tomáš Hudlický, Gabor Butora, Stephen P. Fearnley et al. · Journal of the Chemical Society Perkin Transactions 1 · 1995 · 32 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16

Chemoenzymatic synthesis of the morphine skeleton via radical cyclization and a C10C11 closure

Gabor Butora, Tomáš Hudlický, Stephen P. Fearnley et al. · Tetrahedron Letters · 1996 · 29 citations

Pharmacy, Chemistry, Medicinal Chemistry +13