David S. Middlemas

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

Dan Soppet, Enrique Escandón, Johnne Maragos et al. · Cell · 1991 · 822 citations

Life Sciences, Molecular Biology, Neuroscience +10

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

David S. Middlemas, Richard Lindberg, Tony Hunter · Molecular and Cellular Biology · 1991 · 778 citations · Full text

Life Sciences, Molecular Biology, Neurobiology +8

Increased production of the TrkB protein tyrosine kinase receptor after brain insults

Jean‐Philippe Merlio, Patrik Ernfors, Zaal Kokaia et al. · Neuron · 1993 · 345 citations

Life Sciences, Molecular Biology, Neuroscience +14

Human Immunodeficiency Virus Protease Inhibitors Serve as Substrates for Multidrug Transporter Proteins MDR1 and MRP1 but Retain Antiviral Efficacy in Cell Lines Expressing These Transporters

R V Srinivas, David S. Middlemas, Pat Flynn et al. · Antimicrobial Agents and Chemotherapy · 1998 · 145 citations · Full text

Medicine, Infectious Diseases, Pharmacology +15

Increased levels of trkB mRNA and trkB protein-like immunoreactivity in the injured rat and cat spinal cord.

Jonas Frisén, Valerie M. K. Verge, Staffan Cullheim et al. · Proceedings of the National Academy of Sciences · 1992 · 132 citations · Full text

Medicine, Neurobiology, Neuroscience +17