David S. Middlemas

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

Dan Soppet, Enrique Escandón, Johnne Maragos et al. · Cell · 1991 · 820 citations

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +6

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

David S. Middlemas, Richard Lindberg, Tony Hunter · Molecular and Cellular Biology · 1991 · 777 citations · Full text

Trkb Gene, Synaptic Transmission, Synaptic Signaling +16

Increased production of the TrkB protein tyrosine kinase receptor after brain insults

Jean‐Philippe Merlio, Patrik Ernfors, Zaal Kokaia et al. · Neuron · 1993 · 345 citations

Signal Transduction, Receptor Tyrosine Kinase, Neuropharmacology +8

Human Immunodeficiency Virus Protease Inhibitors Serve as Substrates for Multidrug Transporter Proteins MDR1 and MRP1 but Retain Antiviral Efficacy in Cell Lines Expressing These Transporters

R V Srinivas, David S. Middlemas, Pat Flynn et al. · Antimicrobial Agents and Chemotherapy · 1998 · 145 citations · Full text

Increased levels of trkB mRNA and trkB protein-like immunoreactivity in the injured rat and cat spinal cord.

Jonas Frisén, Valerie M. K. Verge, Staffan Cullheim et al. · Proceedings of the National Academy of Sciences · 1992 · 132 citations

Peripheral Nerve Injury, Cat Spinal Cord, Pathology +18