Celia Sharp

CNTO 95, a fully human monoclonal antibody that inhibits αv integrins, has antitumor and antiangiogenic activity <i>in vivo</i>

Mohit Trikha, Zhou Zhao, Jeffrey A. Nemeth et al. · International Journal of Cancer · 2004 · 153 citations

Immunology, Pathology, Immunotherapeutics +18

Synthesis of thiophene-2-carboxamidines containing 2-amino-thiazoles and their biological evaluation as urokinase inhibitors

Kenneth J. Wilson, Carl R. Illig, Nalin L. Subasinghe et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 98 citations · Full text

Medicinal Chemistry, Biochemistry, Urokinase Inhibitors +9

CNTO 95, a fully human anti αv integrin antibody, inhibits cell signaling, migration, invasion, and spontaneous metastasis of human breast cancer cells

Qiming Chen, Carol D. Manning, Hillary J. Millar et al. · Clinical & Experimental Metastasis · 2007 · 86 citations

Breast Oncology, Cnto 95, Spontaneous Metastasis +10

Design and Synthesis of 4,5-Disubstituted-thiophene-2-amidines as Potent Urokinase Inhibitors

Matthias Rudolph, Carl R. Illig, Nalin L. Subasinghe et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 31 citations · Full text

Medicinal Chemistry, Medicine, Potent Urokinase Inhibitors +5

Structure-Based design, synthesis and sAR of a novel series of thiopheneamidine urokinase plasminogen activator inhibitors

Nalin L. Subasinghe, Carl R. Illig, James B. Hoffman et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 14 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Novel Series +9