Werner Gladdines

Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx,®/Doxil®—A Cerebral Open Flow Microperfusion Pilot Study

Thomas Birngruber, Reingard Raml, Werner Gladdines et al. · Journal of Pharmaceutical Sciences · 2014 · 115 citations

Nanomedicine, Engineering, Medicine +13

Glutathione PEGylated liposomal methylprednisolone (2B3-201) attenuates CNS inflammation and degeneration in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis

De-Hyung Lee, Caroline Rötger, Chantal C.M. Appeldoorn et al. · Journal of Neuroimmunology · 2014 · 50 citations

Inflammation, Autoimmune Disease, Cns Inflammation +11

Patient-reported adverse effects of high-dose intravenous methylprednisolone treatment: a prospective web-based multi-center study in multiple sclerosis patients with a relapse

Peter Joseph Jongen, I. Stavrakaki, Bernard Voet et al. · Journal of Neurology · 2016 · 43 citations · Full text

Daily Living, Multiple Sclerosis Patients, Neurological Disorder +13

Abstract CT216: Phase I dose escalating study of 2B3-101, glutathione PEGylated liposomal doxorubicin, in patients with solid tumors and brain metastases or recurrent malignant glioma

Pieter J. Gaillard, Bojana Milojkovic Kerklaan, Philippe Aftimos et al. · Cancer Research · 2014 · 37 citations

Pharmacotherapy, High-grade Gliomas, Glioma +19

High-performance liquid chromatography of the neuroactive steroids alphaxalone and pregnanolone in plasma using dansyl hydrazine as fluorescent label: application to a pharmacokinetic-pharmacodynamic study in rats

Sandra A. G. Visser, Chantal Smulders, Werner Gladdines et al. · Journal of Chromatography B Biomedical Sciences and Applications · 2000 · 37 citations

Fluorescent Label, Pharmacological Study, Medicine +8