William T. Comer

Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

Maria Z. Kounnas, Anne M. Danks, Soan Cheng et al. · Neuron · 2010 · 251 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Degenerative Pathology +5

Antihypertensive agents. Synthesis and biological properties of 2-amino-4-aryl-2-imidazolines

W. L. Matier, D. Alfred Owens, William T. Comer et al. · Journal of Medicinal Chemistry · 1973 · 133 citations

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +13

Antihypertensive indole derivatives of phenoxypropanolamines with .beta.-adrenergic receptor antagonist and vasodilating activity

W. E. Kreighbaum, W. L. Matier, Ronald D. Dennis et al. · Journal of Medicinal Chemistry · 1980 · 46 citations

Vasodilating Activity, Hypertension, Pharmacotherapy +17

Sulfonanilides. II. Analogs of Catecholamines

A. A. Larsen, William A. Gould, Herbert R. Roth et al. · Journal of Medicinal Chemistry · 1967 · 41 citations

Therapeutic Drug Monitoring, Medicinal Chemistry, Pharmacological Study +11

NGP 555, a γ‐secretase modulator, lowers the amyloid biomarker, Aβ _42, in cerebrospinal fluid while preventing Alzheimer's disease cognitive decline in rodents

Maria Z. Kounnas, Courtney Lane‐Donovan, Dan W. Nowakowski et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions · 2016 · 34 citations · Full text