Jacob Irwin

Techniques for monitoring protein misfolding and aggregation in vitro and in living cells

Simpson Gregoire, Jacob Irwin, Inchan Kwon · Korean Journal of Chemical Engineering · 2012 · 68 citations · Full text

Living Cells, Protein Assembly, Protein Folding +9

Targeting of Heparanase-modified Syndecan-1 by Prosecretory Mitogen Lacritin Requires Conserved Core GAGAL plus Heparan and Chondroitin Sulfate as a Novel Hybrid Binding Site That Enhances Selectivity

Yinghui Zhang, Ningning Wang, Ronald W. Raab et al. · Journal of Biological Chemistry · 2013 · 37 citations · Full text

Different Fates of Alzheimer’s Disease Amyloid-β Fibrils Remodeled by Biocompatible Small Molecules

Jacob Irwin, H. Edward Wong, Inchan Kwon · Biomacromolecules · 2012 · 29 citations

Neurochemical Biomarkers, Biomedical Engineering, Biocompatible Small Molecules +16

Halogenation Generates Effective Modulators of Amyloid-Beta Aggregation and Neurotoxicity

H. Edward Wong, Jacob Irwin, Inchan Kwon · PLoS ONE · 2013 · 20 citations · Full text

Erb Analogs, Peptide Engineering, Neurochemical Biomarkers +19

Oral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model

Jacob Irwin, Alev Erişir, Inchan Kwon · Current Alzheimer Research · 2016 · 20 citations · Full text

Neurotransmitter, Optogenetics, Appswdi/nos2-/- Mouse Model +19