STING directly activates autophagy to tune the innate immune response

Dong Liu, Hao Wu, Chenguang Wang, +10

Cell Death and Differentiation

InflammationCell AutophagyHost ResponseAutoimmune DiseasePathogenesis +10

N6-methyladenosine RNA modification suppresses antiviral innate sensing pathways via reshaping double-stranded RNA

Weinan Qiu, Qingyang Zhang, Rui Zhang, +15

Nature Communications

Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms

Yongzhi Chen, Shanshan Wang, Zhaohong Yi, +12

Scientific Reports

PPM1G restricts innate immune signaling mediated by STING and MAVS and is hijacked by KSHV for immune evasion

Kuai Yu, Huabin Tian, Hongyu Deng

Science Advances

NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos

Fang-Nong Lai, Lijia Li, Xiaoyu Hu, +14

Cell Research

Identification of new type I interferon-stimulated genes and investigation of their involvement in IFN-β activation

Xiaolin Zhang, Wei Yang, Xinlu Wang, +5

Protein & Cell

New TypeIfn-β ActivationImmunologyViral PathogenesisInnate Immunity +18

Structural basis for Sarbecovirus ORF6 mediated blockage of nucleocytoplasmic transport

Xiaopan Gao, Huabin Tian, Kaixiang Zhu, +6

Nature Communications

Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10

Han Feng, Huabin Tian, Yong Wang, +6

Proceedings of the National Academy of Sciences

Identification of the Immunogenic Outer Membrane Protein A Antigen of Haemophilus parasuis by a Proteomics Approach and Passive Immunization with Monoclonal Antibodies in Mice

Huabin Tian, Fang Fu, Xuesong Li, +7

Clinical and Vaccine Immunology

HistocompatibilityPassive ImmunizationImmunologyImmunodominanceAntigen Processing +17

RNF213 modulates γ-herpesvirus infection and reactivation via targeting the viral Replication and Transcription Activator

Huabin Tian, Kuai Yu, Liang He, +8

Proceedings of the National Academy of Sciences