The Formin DAD Domain Plays Dual Roles in Autoinhibition and Actin Nucleation

Christopher J. Gould, Sankar Maiti, Alphée Michelot, +3

Current Biology

Protein FunctionActin NucleationMolecular RegulationMolecular BiologyCytoskeleton +4

A module for Rac temporal signal integration revealed with optogenetics

Brian R. Graziano, Delquin Gong, Karen E. Anderson, +3

The Journal of Cell Biology

Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

Brian R. Graziano, Jason P. Town, E Sitarska, +8

PLoS Biology

Migratory CellsPolarity ComponentsMolecular BiologyCytoskeletonCell Confinement +14

Mechanism and cellular function of Bud6 as an actin nucleation–promoting factor

Brian R. Graziano, Amy Grace DuPage, Alphée Michelot, +5

Molecular Biology of the Cell

Actin Nucleation–promoting FactorMolecular BiologyCytoskeletonCellular PhysiologyFormin Activity +16

The WAVE complex associates with sites of saddle membrane curvature

Anne Pipathsouk, Rachel M. Brunetti, Jason P. Town, +7

The Journal of Cell Biology

Cell MorphogenesisEngineeringSurface WaveCytoskeletonSaddle Membrane Curvature +19

Ligand-induced activation of a formin–NPF pair leads to collaborative actin nucleation

Brian R. Graziano, Erin M. Jonasson, Jessica G. Pullen, +2

The Journal of Cell Biology

Protein AssemblyMolecular RegulationGeneticsFormin–npf PairMolecular Biology +22

The F-BAR protein Hof1 tunes formin activity to sculpt actin cables during polarized growth

Brian R. Graziano, Hoi-Ying Elsie Yu, Salvatore L. Alioto, +5

Molecular Biology of the Cell

Protein SecretionProtein AssemblyMolecular BiologyCytoskeletonActin Cables +18

Structure of the formin-interaction domain of the actin nucleation-promoting factor Bud6

Daqi Tu, Brian R. Graziano, Eunyoung Park, +4

Proceedings of the National Academy of Sciences

Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif

Eunyoung Park, Brian R. Graziano, Wei Zheng, +3

Structure

Bud6/actin ComplexSignal TransductionProtein FunctionNatural SciencesMolecular Biology +9

A size-invariant bud-duration timer enables robustness in yeast cell size control

Corey AH Allard, Franziska Decker, Orion D. Weiner, +2

PLoS ONE

Cell ProliferationCell CycleCell GrowthCellular PhysiologyYeast +14