Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy

Marie-Ève Wedge, Victoria A. Jennings, Mathieu J. F. Crupi, +42

Nature Communications

Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model

Joanna Poutou, María Buñuales, Manuela González-Aparicio, +6

Gene Therapy

Characterization of Critical Determinants of ACE2–SARS CoV-2 RBD Interaction

Emily E. F. Brown, Reza Rezaei, Taylor R. Jamieson, +20

International Journal of Molecular Sciences

110. Safety and Antitumor Effect of Oncolytic and Helper-Dependent Adenoviruses Expressing Interleukin-12 Variants in a Hamster Pancreatic Cancer Model

Joanna Poutou, María Buñuales, Manuela Caballero González, +6

Molecular Therapy

ImmunologyImmunoeditingPathologyImmunotherapyTumor Biology +17

Capsid-deficient alphaviruses generate propagative infectious microvesicles at the plasma membrane

Marta Ruiz-Guillen, Evgeni Evgeniev Gabev, José I. Quetglas, +11

Cellular and Molecular Life Sciences

Virus StructureViral ReplicationPathogenesisViral PathogenesisVirology +4

Inhibition of adenovirus infection by mifepristone

José Antonio Marrugal‐Lorenzo, Ana Serna‐Gallego, Loreto González-González, +6

Antiviral Research

Adenovirus InfectionMedicineAntiviral Drug DevelopmentVirologyAntiviral Drug +2

Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry

Taha Azad, Ragunath Singaravelu, Zaid Taha, +21

Molecular Therapy

Viral ReplicationSynthetic VirologyGlycobiologyViral PathogenesisImmunology +16

Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization

Taha Azad, Ragunath Singaravelu, Mathieu J. F. Crupi, +17

Membranes

VaccinationViral EvolutionVaccine DevelopmentSpike TrimerizationVaccine Target +10

Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection

Stephen Boulton, Joanna Poutou, Nikolas T. Martin, +28

Molecular Therapy

Recombinant in vitro assembled hepatitis C virus core particles induce strong specific immunity enhanced by formulation with an oil-based adjuvant

Nelson Acosta‐Rivero, Joanna Poutou, Liz Alvarez‐Lajonchere, +13

Biological Research