Azide and Cyanide Displacements via Hypervalent Silicate Intermediates

Eric D. Soli, Amy S. Manoso, Michael C. Patterson, +4

The Journal of Organic Chemistry

Materials ScienceInorganic ChemistryChemical EngineeringTrimethylsilyl AzideEngineering +13

Total Synthesis of (+)-Azaspiracid-1. An Exhibition of the Intricacies of Complex Molecule Synthesis

David A. Evans, Lisbet Kværnø, Travis B. Dunn, +7

Journal of the American Chemical Society

Medicinal ChemistrySulfone Anion MethodologiesBioorganic ChemistryBiochemistryNatural Sciences +13

Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window

Joachim Rudolph, Lesley Murray, Chudi Ndubaku, +26

Journal of Medicinal Chemistry

Cardiovascular PharmacologyPharmacotherapyCardiovascular ToxicityDiverse GroupTumor Biology +16

Total Synthesis of (+)‐Azaspiracid‐1. Part II: Synthesis of the EFGHI Sulfone and Completion of the Synthesis

David A. Evans, Travis B. Dunn, Lisbet Kværnø, +7

Angewandte Chemie International Edition

Statistical ReviewPlease NoteEngineeringData ScienceMedicine +11

Molecular modeling, synthesis, and structures of N-methylated 3,5-linked pyrrolin-4-ones toward the creation of a privileged nonpeptide scaffold

Amos B. Smith, David A. Favor, Paul A. Sprengeler, +4

Bioorganic & Medicinal Chemistry

Discovery of PF-00217830: Aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder

Douglas S. Johnson, Chung Sik Choi, Lorraine K. Fay, +10

Bioorganic & Medicinal Chemistry Letters

Psychoactive DrugPsychiatryMedicineDrug DiscoveryPsychopharmacology +7

A second-generation synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones: Incorporation of functionalized amino acid side-chains

Amos B. Smith, Andrew B. Benowitz, David A. Favor, +2

Tetrahedron Letters

Bioorganic ChemistryOrganic ChemistryPeptide ScienceFunctionalized Imino EstersChemistry +17

Synthesis of Polypyrrolinones on Solid Support

Amos B. Smith, Hu Liu, Hiroyuki Okumura, +2

Organic Letters

Synthesis of chromanyl and dihydrobenzofuranyl piperazines

David A. Favor, Douglas S. Johnson, James J. Powers, +2

Tetrahedron Letters

Organic ChemistryHeterocyclicDihydrobenzofuranyl Piperazines

Synthesis of monofluorinated 1-(naphthalen-1-yl)piperazines

Joseph T. Repine, Douglas S. Johnson, Andrew D. White, +6

Tetrahedron Letters

Organic ChemistryChemistryHeterocycle Chemistry