Oxygen Self-Sufficient Core–Shell Metal–Organic Framework-Based Smart Nanoplatform for Enhanced Synergistic Chemotherapy and Photodynamic Therapy

Shen‐Zhen Ren, Bin Wang, Xiaohua Zhu, +6

ACS Applied Materials & Interfaces

Nanoscale Metal–Organic-Frameworks Coated by Biodegradable Organosilica for pH and Redox Dual Responsive Drug Release and High-Performance Anticancer Therapy

Shen‐Zhen Ren, Dan Zhu, Xiaohua Zhu, +7

ACS Applied Materials & Interfaces

NanoparticlesNanomedicineEngineeringHigh-performance Anticancer TherapyNanomaterials +13

Coumarin sulfonamides derivatives as potent and selective COX-2 inhibitors with efficacy in suppressing cancer proliferation and metastasis

Xiaoyuan Lu, Zhong‐Chang Wang, Shen‐Zhen Ren, +3

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryCancer ProliferationMedicinePharmacologySelective Cox-2 Inhibitors +7

Design, synthesis and biological evaluation of novel ferrocene-pyrazole derivatives containing nitric oxide donors as COX-2 inhibitors for cancer therapy

Shen‐Zhen Ren, Zhong‐Chang Wang, Dan Zhu, +6

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryNitric Oxide DonorsCox-2 InhibitorsDrug Discovery +7

Arylamino containing hydroxamic acids as potent urease inhibitors for the treatment of Helicobacter pylori infection

Qi Liu, Wei-Kang Shi, Shen‐Zhen Ren, +11

European Journal of Medicinal Chemistry

Hydroxamic AcidsHealth SciencesMedicineAntibiotic AdjuvantAntibacterial Agent +9

Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX

Fa-Qian Shen, Zhong‐Chang Wang, Songyu Wu, +4

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDual InhibitorsMedicineDrug DiscoveryNovel Hybrids +6

Discovery of a series of 1,3,4-oxadiazole-2(3H)-thione derivatives containing piperazine skeleton as potential FAK inhibitors

Juan Sun, Shen‐Zhen Ren, Xiaoyuan Lu, +4

Bioorganic & Medicinal Chemistry

Multifunctional Protein Hybrid Nanoplatform for Synergetic Photodynamic‐Chemotherapy of Malignant Carcinoma by Homologous Targeting Combined with Oxygen Transport

Songyu Wu, Ya‐Xi Ye, Qing Zhang, +11

Advanced Science

NanotherapeuticsHomologous Targeting CombinedTumor BiologyDrug ResistanceNanomedicine +18

Design, synthesis and evaluation of novel diaryl-1,5-diazoles derivatives bearing morpholine as potent dual COX-2/5-LOX inhibitors and antitumor agents

Zhang Li, Zhong‐Chang Wang, Xin Li, +9

European Journal of Medicinal Chemistry

Medicinal ChemistryAntitumor AgentsMedicinePharmacotherapyAnti-cancer Agent +6

Design and biological evaluation of novel hybrids of 1, 5-diarylpyrazole and Chrysin for selective COX-2 inhibition

Shen‐Zhen Ren, Zhong‐Chang Wang, Xiaohua Zhu, +7

Bioorganic & Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryBiochemistrySelective Cox-2 Inhibition +8