Brad J. Nolen

Characterization of two classes of small molecule inhibitors of Arp2/3 complex

Brad J. Nolen, Nenad Tomas̆ević, Alan J. Russell et al. · Nature · 2009 · 542 citations · Full text

Molecular Docking, Small Molecule Inhibitors, Biochemistry +10

Small Molecules CK-666 and CK-869 Inhibit Actin-Related Protein 2/3 Complex by Blocking an Activating Conformational Change

Byron Hetrick, Min Suk Han, Luke A. Helgeson et al. · Chemistry & Biology · 2013 · 355 citations · Full text

Small Molecules Ck-666, Activating Conformational Change, Protein Function +13

Interplay between SRPK and Clk/Sty Kinases in Phosphorylation of the Splicing Factor ASF/SF2 Is Regulated by a Docking Motif in ASF/SF2

Jacky Chi Ki Ngo, Sutapa Chakrabarti, Jianhua Ding et al. · Molecular Cell · 2005 · 206 citations · Full text

Signal Transduction, Signaling Pathway, Docking Motif +10

Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex

Shih-Chieh Ti, Christopher T. Jurgenson, Brad J. Nolen et al. · Proceedings of the National Academy of Sciences · 2011 · 141 citations

Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP

Luke A. Helgeson, Brad J. Nolen · eLife · 2013 · 129 citations · Full text