Concepedia

Author

Gernot Polier

German Cancer Research Center

Also Known As

G Polier, Gernot Polier

8

Publications

568

Citations

6

H-Index

15

Concepts

All Affiliations

German Cancer Research CenterHeidelberg UniversityLaboratoire d'Innovation Thérapeutique
GP

About

Gernot Polier is an author at German Cancer Research Center specializing in tumor biology, cancer research, and medicine.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

2

2

218

2

Pharmacology

2

2

218

3

Natural Sciences

1

1

158

4

Biochemistry

1

1

158

5

Immunology

1

1

60

Gernot Polier

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6

Publications

565

Citations

6

H-Index

YearCitations

Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1

Gernot Polier, Jian Ding, V. Badireenath Konkimalla,

Cell Death and Disease

2011

160

The Natural Anticancer Compounds Rocaglamides Inhibit the Raf-MEK-ERK Pathway by Targeting Prohibitin 1 and 2

Gernot Polier, Jennifer Neumann, Frédéric Thuaud,

Chemistry & Biology

2012

158

Wogonin and Related Natural Flavones Overcome Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Protein Resistance of Tumors by Down-regulation of c-FLIP Protein and Up-regulation of TRAIL Receptor 2 Expression

Jie Ding, Gernot Polier, Rebecca Köhler,

Journal of Biological Chemistry

2011

87

High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade

Michael K. Kießling, Patrick A. Oberholzer, Chandrani Mondal,

Blood

2011

74

Targeting CDK9 by wogonin and related natural flavones potentiates the anti‐cancer efficacy of the Bcl‐2 family inhibitor ABT‐263

Gernot Polier, Marco Giaisi, Rebecca Köhler,

International Journal of Cancer

2014

60

A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1

Masashi Numata, Noriyasu Haginoya, Machiko Shiroishi,

Cancer Cell International

2023

26

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