Gernot Polier

Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1

Gernot Polier, Jian Ding, V. Badireenath Konkimalla et al. · Cell Death and Disease · 2011 · 163 citations · Full text

Life Sciences, Oncology, Pharmacology +17

The Natural Anticancer Compounds Rocaglamides Inhibit the Raf-MEK-ERK Pathway by Targeting Prohibitin 1 and 2

Gernot Polier, Jennifer Neumann, Frédéric Thuaud et al. · Chemistry & Biology · 2012 · 161 citations

Medicine, Oncology, Pharmacology +13

Wogonin and Related Natural Flavones Overcome Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Protein Resistance of Tumors by Down-regulation of c-FLIP Protein and Up-regulation of TRAIL Receptor 2 Expression

Jie Ding, Gernot Polier, Rebecca Köhler et al. · Journal of Biological Chemistry · 2011 · 87 citations · Full text

Life Sciences, Oncology, Pharmacology +16

High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade

Michael K. Kießling, Patrick A. Oberholzer, Chandrani Mondal et al. · Blood · 2011 · 77 citations · Full text

Medicine, Genetics, Oncology +17

Targeting CDK9 by wogonin and related natural flavones potentiates the anti‐cancer efficacy of the Bcl‐2 family inhibitor ABT‐263

Gernot Polier, Marco Giaisi, Rebecca Köhler et al. · International Journal of Cancer · 2014 · 61 citations · Full text

Medicine, Oncology, Pharmacology +17