Edward R. Block

Hyperuricemia induces endothelial dysfunction

Uday M. Khosla, Sergey Zharikov, Jennifer Finch et al. · Kidney International · 2005 · 1.2K citations

Hypertension, Hyperthermia, Cardiovascular Disease +6

A causal role for uric acid in fructose-induced metabolic syndrome

Takahiko Nakagawa, Hanbo Hu, Sergey Zharikov et al. · American Journal of Physiology-Renal Physiology · 2005 · 1.1K citations

Metabolic Syndrome, Nutrition, Serum Uric Acid +14

A Caveolar Complex between the Cationic Amino Acid Transporter 1 and Endothelial Nitric-oxide Synthase May Explain the “Arginine Paradox”

Kelly McDonald, S. I. Zharikov, Edward R. Block et al. · Journal of Biological Chemistry · 1997 · 440 citations · Full text

Effect of Cigarette Smoke Extract on Nitric Oxide Synthase in Pulmonary Artery Endothelial Cells

Yunchao Su, Weihong Han, Carlos Giraldo et al. · American Journal of Respiratory Cell and Molecular Biology · 1998 · 330 citations

Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells

Sergey Zharikov, Karina Krotova, Hanbo Hu et al. · American Journal of Physiology-Cell Physiology · 2008 · 239 citations · Full text

Inflammation, Paec Lysates, Arginase Activity +15