Estrogen Prevents the Lipopolysaccharide-Induced Inflammatory Response in Microglia

Elisabetta Vegeto, Cinzia Bonincontro, Giuseppe Pollio, +7

Journal of Neuroscience

Mapping and Characterization of the Functional Domains Responsible for the Differential Activity of the A and B Isoforms of the Human Progesterone Receptor

Paloma H. Giangrande, Giuseppe Pollio, Donald P. McDonnell

Journal of Biological Chemistry

Progesterone ReceptorAmino AcidsGynecologyHuman Progesterone ReceptorTranscriptional Regulation +18

Engineering of a Mouse for the in Vivo Profiling of Estrogen Receptor Activity

Paolo Ciana, Giovanni Di Luccio, Silvia Belcredito, +5

Molecular Endocrinology

An exploratory double‐blind, randomized clinical trial with selisistat, a <scp>SirT1</scp> inhibitor, in patients with <scp>H</scp>untington's disease

Sigurd D. Süßmuth, Salman Haider, G. Bernhard Landwehrmeyer, +25

British Journal of Clinical Pharmacology

A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease

M.R. Smith, Adeela Syed, Tamás Lukácsovich, +23

Human Molecular Genetics

Histone ModificationsCell DeathMolecular BiologyMultiple AnimalTranscriptional Regulation +18

Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3.

Z Q, Sabrina Santagati, Cesare Patrone, +3

Molecular Endocrinology

Human GrowthInsulin-like Growth FactorsEstrogen ReceptorCell GrowthInsulin Signaling +14

Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1

Carla Scali, Filippo Caraci, Marco Gianfriddo, +8

Neurobiology of Disease

Neurodegenerative DiseasesSignal TransductionTau PhosphorylationSignaling PathwayNeuronal Cell Death +9

Estrogen and progesterone induction of survival of monoblastoid cells undergoing TNF‐α‐induced apoptosis

Elisabetta Vegeto, Giuseppe Pollio, C. Pellicciari, +1

The FASEB Journal

Antisense oligonucleotide blocks progesterone-induced lordosis behavior in ovariectomized rats

Giuseppe Pollio, Peifeng Xue, M. Zanisi, +2

Molecular Brain Research

Female InfertilityGynecologyAntisense OligonucleotideEndocrinologyMedicine +1

siRNA screen identifies QPCT as a druggable target for Huntington's disease

María Jiménez-Sánchez, Wun Lam, Michael Hannus, +26

Nature Chemical Biology

Druggable TargetGeneticsMolecular BiologyNeurodegenerationMedicine