Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial

Irene L. M. Reijers, Alexander M. Menzies, Alexander C. J. van Akkooi, +35

Nature Medicine

Surgical OncologyOncologyPrado TrialMelanomaClinical Trials +8

Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets

Felicity Newell, Yan Kong, James S. Wilmott, +41

Nature Communications

Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma

M.T. Tetzlaff, Jane L. Messina, Julie E. Stein, +20

Annals of Oncology

Neoadjuvant dabrafenib combined with trametinib for resectable, stage IIIB–C, BRAFV600 mutation-positive melanoma (NeoCombi): a single-arm, open-label, single-centre, phase 2 trial

Georgina V. Long, Robyn P.M. Saw, Serigne Lo, +19

The Lancet Oncology

Neoadjuvant DabrafenibSurgical OncologyMedicineMelanomaPathology +7

Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity

Felicity Newell, James S. Wilmott, Peter A. Johansson, +32

Nature Communications

Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes

Felicity Newell, Peter A. Johansson, James S. Wilmott, +32

Cancer Discovery

PD-L1 Expression and Immune Escape in Melanoma Resistance to MAPK Inhibitors

Hojabr Kakavand, Robert V. Rawson, Gulietta M. Pupo, +11

Clinical Cancer Research

IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma

Irene L. M. Reijers, Disha Rao, Judith M. Versluis, +23

The Journal of Experimental Medicine

Cancer ImmunosurveillanceMedicineDonimi TrialImmunologyTumor Immunity +13

First safety and efficacy results of PRADO: A phase II study of personalized response-driven surgery and adjuvant therapy after neoadjuvant ipilimumab (IPI) and nivolumab (NIVO) in resectable stage III melanoma.

Christian U. Blank, Irene L. M. Reijers, Thomas E. Pennington, +17

Journal of Clinical Oncology

Surgical OncologyIln ResectionImmunologyPathologySurgery +15

Replacement and desmoplastic histopathological growth patterns in cutaneous melanoma liver metastases: frequency, characteristics, and robust prognostic value

Raymond L. Barnhill, Pieter‐Jan van Dam, Peter Vermeulen, +12

The Journal of Pathology Clinical Research