Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster

Natasha Arora, Verena J. Schuenemann, Günter Jäger, +27

Nature Microbiology

Parasitic DiseaseEmerging Infectious DiseasesModern SyphilisPathologyDisease Emergence +6

Antigenic Variation in <i>Treponema pallidum</i> : TprK Sequence Diversity Accumulates in Response to Immune Pressure during Experimental Syphilis

Lorenzo Giacani, Barbara J. Molini, Eric Y. Kim, +5

The Journal of Immunology

Fine Analysis of Genetic Diversity of the tpr Gene Family among Treponemal Species, Subspecies and Strains

Arturo Centurion‐Lara, Lorenzo Giacani, Charmie Godornes, +3

PLoS neglected tropical diseases

Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar

Nicole A. P. Lieberman, Michelle J. Lin, Hong Xie, +29

PLoS neglected tropical diseases

DNA immunization with pgp3 gene of Chlamydia trachomatis inhibits the spread of chlamydial infection from the lower to the upper genital tract in C3H/HeN mice

Manuela Donati, Vittorio Sambri, Maurizio Comanducci, +5

Vaccine

Pgp3 GeneChlamydia TrachomatisPathogenesisImmunologyMedicine +1

Comparative Investigation of the Genomic Regions Involved in Antigenic Variation of the TprK Antigen among Treponemal Species, Subspecies, and Strains

Lorenzo Giacani, S. Brandt, Maritza Puray‐Chavez, +7

Journal of Bacteriology

Tprk AntigenGenomic Regions InvolvedTprk VariantsTprk Expression SitePathogenesis +13

Quantitative Analysis of<i>tpr</i>Gene Expression in<i>Treponema pallidum</i>Isolates: Differences among Isolates and Correlation with T-Cell Responsiveness in Experimental Syphilis

Lorenzo Giacani, Barbara J. Molini, Charmie Godornes, +4

Infection and Immunity

Complete Genome Sequence and Annotation of the <i>Treponema pallidum</i> subsp. <i>pallidum</i> Chicago Strain

Lorenzo Giacani, Brendan M. Jeffrey, Barbara J. Molini, +4

Journal of Bacteriology

Reverse GeneticsComparative GenomicsNichols StrainPathologyGenomics +15

Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens

Linda Grillová, Jan Oppelt, Lenka Mikalová, +17

Frontiers in Microbiology

Whole Genome Sequence of the Treponema pallidum subsp. endemicum Strain Bosnia A: The Genome Is Related to Yaws Treponemes but Contains Few Loci Similar to Syphilis Treponemes

Barbora Štaudová, Michal Strouhal, Marie Zobaníková, +9

PLoS neglected tropical diseases