Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

Manuela Rossol, Matthias Pierer, Nora Raulien, +11

Nature Communications

The CD14 ^bright CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population

Manuela Rossol, Stephan Kraus, Matthias Pierer, +2

Arthritis & Rheumatism

Chemokine Secretion of Rheumatoid Arthritis Synovial Fibroblasts Stimulated by Toll-Like Receptor 2 Ligands

Matthias Pierer, Janine Rethage, Reinhart Seibl, +8

The Journal of Immunology

InflammationRheumatologyHigh DensityCytokineAnti-inflammatory +13

Post-thymic in vivo proliferation of naive CD4+ T cells constrains the TCR repertoire in healthy human adults

Siegfried Köhler, Ulf Wagner, Matthias Pierer, +6

European Journal of Immunology

Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis

E.J. Jäger, Supriya Murthy, Caroline Schmidt, +24

Nature Communications

Interaction between Transmembrane TNF and TNFR1/2 Mediates the Activation of Monocytes by Contact with T Cells

Manuela Rossol, Undine Meusch, Matthias Pierer, +4

The Journal of Immunology

Association of UCP2 −866 G/A polymorphism with chronic inflammatory diseases

Xinhua Yu, Stefan Wieczorek, André Franke, +13

Genes and Immunity

InflammationChronic Inflammatory DiseasesImmunologyGenetic EpidemiologyChronic Inflammation +9

Toll-Like Receptor 4 Is Involved in Inflammatory and Joint Destructive Pathways in Collagen-Induced Arthritis in DBA1J Mice

Matthias Pierer, Ulf Wagner, Manuela Rossol, +1

PLoS ONE

ImmunologyInnate ImmunityJoint Destructive PathwaysImmune SystemTlr4 Deficient +16

Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients

Matthias Pierer, Sylke Kaltenhäuser, Sybille Arnold, +4

Arthritis Research & Therapy

The TNF superfamily member LIGHT contributes to survival and activation of synovial fibroblasts in rheumatoid arthritis

Matthias Pierer, Fabia Brentano, Janine Rethage, +5

Lara D. Veeken