Novel Benzopyridothiadiazepines as Potential Active Antitumor Agents

Nicolas Lebègue, Sebastien Gallet, Nathalie Flouquet, +7

Journal of Medicinal Chemistry

Medicinal ChemistryPharmaceutical ScienceNovel BenzopyridothiadiazepinesMedicinePharmacological Agent +11

Synthesis of a novel series of (Z)-3,5-disubstituted thiazolidine-2,4-diones as promising anti-breast cancer agents

Hussein El‐Kashef, Gamal Badr, Nagwa Abo El‐Maali, +4

Bioorganic Chemistry

Medicinal ChemistryHeterocyclicNovel SeriesNatural SciencesMedicine +5

Docking Study of Ligands into the Colchicine Binding Site of Tubulin

Amaury Farce, Cédric Logé, Sebastien Gallet, +5

Journal of Enzyme Inhibition and Medicinal Chemistry

Protein AssemblyMolecular BiologyCytoskeletonChemical BiologyMedicinal Chemistry +19

Synthesis of triazoloquinazolinone based compounds as tubulin polymerization inhibitors and vascular disrupting agents

Mohsine Driowya, Julien Leclercq, Valérie Verones, +7

European Journal of Medicinal Chemistry

Medicinal ChemistryVascular Disrupting AgentsPharmacologyTubulin Polymerization InhibitorsPharmacotherapy +4

Scavenging of reactive oxygen species by letosteine, a molecule with two blocked -SH groups

Bernard Gressier, Nicolas Lebègue, C. Brunet, +4

Pharmacy World & Science

Combinatorial ChemistryBioorganic ChemistryHeterocyclicBiochemistryMedicine +8

Efficient and selective deprotection method for N-protected 2(3H)-benzoxazolones and 2(3H)-benzothiazolones

Pascal Carato, Didier Sellier, Jacques H. Poupaert, +2

Tetrahedron

MedicineOrganic ChemistrySelective Deprotection MethodPharmacologyPharmaceutical Chemistry +2

Emerging paradigms and recent progress in targeting ErbB in cancers

Nicolas Stoup, Maxime Liberelle, Nicolas Lebègue, +1

Trends in Pharmacological Sciences

Synthesis, antiproliferative activity and tubulin targeting effect of acridinone and dioxophenothiazine derivatives

Valérie Verones, Nathalie Flouquet, Marie Lecoeur, +9

European Journal of Medicinal Chemistry

BiochemistryAntiproliferative ActivityMedicineDioxophenothiazine DerivativesMechanism Of Action +5

A mild and efficient route to 2-benzyl tryptamine derivatives via ring-opening of β-carbolines

Fariza Hadjaz, Nicolas Lebègue, Pascal Berthelot, +1

Tetrahedron

Combinatorial ChemistryDerivativesEfficient RouteOrganic ChemistryChemistry +4

Synthesis and Biological Evaluation of <i>N</i>-[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity

Zacharie Segaoula, Julien Leclercq, Valérie Verones, +9

Journal of Medicinal Chemistry

Tricyclic AnaloguesPharmaceutical SciencePharmacotherapyPharmaceutical ChemistryTumor Biology +16