Keith Nangle

An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People

Matthew R. Nelson, Daniel Wegmann, Margaret G. Ehm et al. · Science · 2012 · 702 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations

Arlene R. Hughes, Michael Mosteller, Aruna T. Bansal et al. · Pharmacogenomics · 2004 · 255 citations

Life Sciences, Genetics, Immunology +15

Emergence of Resistance in HIV-1 Integrase with Dolutegravir Treatment in a Pediatric Population from the IMPAACT P1093 Study

Cindy Vavro, Theodore Ruel, Andrew Wiznia et al. · Antimicrobial Agents and Chemotherapy · 2021 · 34 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Deep Resequencing Unveils Genetic Architecture of <i>ADIPOQ</i> and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation

Liling Warren, Li Li, Matthew R. Nelson et al. · Diabetes · 2012 · 33 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Deep sequencing of the<i>LRRK2</i>gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe

Justin P. Rubio, Simon Topp, Liling Warren et al. · Human Mutation · 2012 · 28 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15