Simon Topp

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

Elizabeth T. Cirulli, Brittany N. Lasseigne, Slavé Petrovski et al. · Science · 2015 · 981 citations · Full text

Life Sciences, Neurology, Neuroscience +17

An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People

Matthew R. Nelson, Daniel Wegmann, Margaret G. Ehm et al. · Science · 2012 · 702 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

Wouter van Rheenen, Aleksey Shatunov, Annelot M. Dekker et al. · Nature Genetics · 2016 · 628 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Cloning and functional expression of a human orthologue of rat vanilloid receptor-1

Philip D. Hayes, H.J. Meadows, Martin J. Gunthorpe et al. · Pain · 2000 · 310 citations

Life Sciences, Molecular Biology, Pharmacology +16

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis

Kevin P. Kenna, Perry T.C. van Doormaal, Annelot M. Dekker et al. · Nature Genetics · 2016 · 294 citations · Full text

Life Sciences, Molecular Genetics, Neuroscience +10