Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile

Laura Ielo, Batel Deri, Maria Paola Germanò, +10

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBiochemistryNatural SciencesMedicine +7

Homologation chemistry with nucleophilic α-substituted organometallic reagents: chemocontrol, new concepts and (solved) challenges

Laura Castoldi, Serena Monticelli, Raffaele Senatore, +2

Chemical Communications

Telescoped, Divergent, Chemoselective C1 and C1‐C1 Homologation of Imine Surrogates: Access to Quaternary Chloro‐ and Halomethyl‐Trifluoromethyl Aziridines

Laura Ielo, Saad Touqeer, Alexander Roller, +3

Angewandte Chemie International Edition

Weinreb Amides as Privileged Acylating Agents for Accessing α-Substituted Ketones

Raffaele Senatore, Laura Ielo, Serena Monticelli, +2

Synthesis

Weinreb AmidesEngineeringBiochemistryNatural SciencesWeinreb Amides 4 +10

Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments

Stefania Ferro, Batel Deri, Maria Paola Germanò, +9

Journal of Medicinal Chemistry

Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors

Stefania Ferro, Laura De Luca, Maria Paola Germanò, +7

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryPiperidine FragmentBiochemistryNatural Sciences +8

Expeditious and Chemoselective Synthesis of α-Aryl and α-Alkyl Selenomethylketones via Homologation Chemistry

Raffaele Senatore, Laura Castoldi, Laura Ielo, +2

Organic Letters

Chemical EngineeringChemoselective SynthesisEngineeringEasy Selenium/lithium ExchangeHomologation Tactics +10

Syntheses, reactivity, and biological applications of coumarins

Andrea Citarella, Serena Vittorio, Christian Dank, +1

Frontiers in Chemistry

Pharmaceutical ScienceBioorganic ChemistryPeptide ScienceChemical BiologyPharmaceutical Chemistry +18

Chemoselective Homologation–Deoxygenation Strategy Enabling the Direct Conversion of Carbonyls into (<i>n+1</i>)-Halomethyl-Alkanes

Margherita Miele, Andrea Citarella, Thierry Langer, +5

Organic Letters

Carbenoid-Mediated Homologation Tactics for Assembling (Fluorinated) Epoxides and Aziridines

Laura Ielo, Vittorio Pace, Veronica Pillari, +2

Synlett

Homologation StrategiesEngineeringAlkene MetathesisNatural SciencesDiversity-oriented Synthesis +9