Aishath Naeem

Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance

Aishath Naeem, Filippo Utro, Qing Wang et al. · Blood Advances · 2022 · 79 citations · Full text

Medicine, Oncology, Pharmacology +14

AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation

Aishath Naeem, Yanan Zhu, Wei‐Li Di et al. · Cell Death and Differentiation · 2015 · 72 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia

Ishwarya Murali, Siddha Kasar, Aishath Naeem et al. · Blood · 2021 · 62 citations · Full text

Life Sciences, Cell Biology, Oncology +16

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis

Aishath Naeem, Cristina Tommasi, Christian Cole et al. · Journal of Allergy and Clinical Immunology · 2016 · 47 citations · Full text

Medicine, Dermatology, Molecular Biology +14

Orchestrated control of filaggrin–actin scaffolds underpins cornification

Danuta Gutowska‐Owsiak, Jorge Bernardino de la Serna, Marco Fritzsche et al. · Cell Death and Disease · 2018 · 47 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17