Josephraj Sophia

Nimbolide upregulates RECK by targeting miR-21 and HIF-1α in cell lines and in a hamster oral carcinogenesis model

Kowshik Jaganathan, Rajakishore Mishra, Josephraj Sophia et al. · Scientific Reports · 2017 · 139 citations · Full text

Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancer

Josephraj Sophia, Kowshik Jaganathan, Anju Dwivedi et al. · Cell Death and Disease · 2018 · 125 citations · Full text

Nimbolide, a neem limonoid inhibits Phosphatidyl Inositol-3 Kinase to activate Glycogen Synthase Kinase-3β in a hamster model of oral oncogenesis

Josephraj Sophia, Kranthi Kiran Kishore Tanagala, Kowshik Jaganathan et al. · Scientific Reports · 2016 · 44 citations · Full text

Blueberry inhibits invasion and angiogenesis in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral squamous cell carcinogenesis in hamsters via suppression of TGF-β and NF-κB signaling pathways

Abdul Basit Baba, Kowshik Jaganathan, Jayaraman Krishnaraj et al. · The Journal of Nutritional Biochemistry · 2016 · 32 citations

Oncology, Chemoprevention Strategy, Nf-κb Signaling Pathways +9

Activation of PI3K/Akt/NF-kB Signaling Mediates Swedish Snus Induced Proliferation and Apoptosis Evasion in the Rat Forestomach: Modulation by Blueberry

Singaraj Ranjani, Kowshik Jaganathan, Josephraj Sophia et al. · Anti-Cancer Agents in Medicinal Chemistry · 2019 · 15 citations