Timothy A. Wiles

Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion

Thomas Delong, Timothy A. Wiles, Rocky L. Baker et al. · Science · 2016 · 481 citations · Full text

<i>Drosophila</i>Muller F Elements Maintain a Distinct Set of Genomic Properties Over 40 Million Years of Evolution

Wilson Leung, C. Shaffer, Laura K Reed et al. · G3 Genes Genomes Genetics · 2015 · 100 citations · Full text

An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse

Timothy A. Wiles, Thomas Delong, Rocky L. Baker et al. · Journal of Autoimmunity · 2016 · 83 citations · Full text

Endogenous Antigen, Autoimmune Disease, Insulin Management +11

Identification of Hybrid Insulin Peptides (HIPs) in Mouse and Human Islets by Mass Spectrometry

Timothy A. Wiles, Roger Powell, Cole R. Michel et al. · Journal of Proteome Research · 2018 · 73 citations · Full text

Immunology, Antigen Processing, Insulin Signaling +20

CD4 T Cells Reactive to Hybrid Insulin Peptides Are Indicators of Disease Activity in the NOD Mouse

Rocky L. Baker, Braxton L. Jamison, Timothy A. Wiles et al. · Diabetes · 2018 · 65 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +26