Phosphorylation of Immunity-Related GTPases by a Toxoplasma gondii-Secreted Kinase Promotes Macrophage Survival and Virulence

Sarah J. Fentress, Michael S. Behnke, Ildikò Rita Dunay, +12

Cell Host & Microbe

InflammationSignal TransductionPathogenesisImmunologyCell Death +7

Toxoplasma gondii Rhoptry Kinase ROP16 Activates STAT3 and STAT6 Resulting in Cytokine Inhibition and Arginase-1-Dependent Growth Control

Barbara A. Butcher, Barbara A. Fox, Leah M. Rommereim, +6

PLoS Pathogens

Type II Toxoplasma gondii<i>KU80</i>Knockout Strains Enable Functional Analysis of Genes Required for Cyst Development and Latent Infection

Barbara A. Fox, Alejandra Falla, Leah M. Rommereim, +6

Eukaryotic Cell

Microbial PathogensAdaptive Immune SystemGeneticsLatent InfectionImmunology +29

The Toxoplasma gondii Rhoptry Kinome Is Essential for Chronic Infection

Barbara A. Fox, Leah M. Rommereim, Rebekah B. Guevara, +4

mBio

Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon

Barbara A. Fox, Rebekah B. Guevara, Leah M. Rommereim, +10

mBio

Intravacuolar Membranes Regulate CD8 T Cell Recognition of Membrane-Bound Toxoplasma gondii Protective Antigen

Jodie Lopez, Amina Bittame, Céline Massera, +15

Cell Reports

Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity

Barbara A. Fox, Kiah L. Sanders, Leah M. Rommereim, +2

PLoS Genetics

ImmunologyPathologyCell DeathImmunodominancePathogen Effector +23

Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii

Anurag Shukla, Kellen Olszewski, Manuel Llinás, +8

International Journal for Parasitology

Optimal Asexual GrowthCell DivisionMature Tissue CystsPathologyMedicine +2

Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii

Leah M. Rommereim, Valéria Bellini, Barbara A. Fox, +8

PLoS ONE

Dense GranulesMicrobial PathogensGeneticsImmunologyPathology +19

Secreted Toxoplasma gondii molecules interfere with expression of MHC-II in interferon gamma-activated macrophages

Louis‐Philippe Leroux, Dayal Dasanayake, Leah M. Rommereim, +4

International Journal for Parasitology

InflammationCytokineImmunologyToxoplasma Gondii MoleculesImmunologic Mechanism +8